OTC Meds: How to Choose Wisely & Safely! (2026)

Choosing Over-the-Counter Medications: A Wise and Safe Approach

Over-the-counter (OTC) medications have become a convenient and accessible way for individuals to manage minor ailments without seeking medical advice. While some OTC drugs were initially prescribed, they have now been deemed safe for self-medication. Others, like paracetamol, have always been available over the counter but are subject to purchase restrictions. However, the safe and effective use of all OTCs requires common sense and responsibility. Several commonly used OTC drugs carry a real risk of dependence, misuse, or harm when taken in higher-than-recommended doses, for longer than needed, or for the wrong reasons.

One notable example is codeine, an opioid medicine used to treat mild to moderate pain and, in some formulations, to suppress coughing. Over the counter, it is often combined with either ibuprofen or paracetamol. Once swallowed, the body converts codeine into morphine, producing its pain-relieving effects. Common side-effects include drowsiness, constipation, nausea, and dizziness. At higher doses, codeine can slow breathing and impair coordination. With repeated use, the body can become tolerant to codeine, meaning the same dose no longer provides the same relief. This process occurs as the brain's opioid receptors adapt to the drug. People may then increase their dose, raising the risk of physical dependence. Stopping suddenly can cause withdrawal symptoms such as anxiety, restlessness, sweating, and sleep problems.

A recent memorandum from the Health Service Executive (HSE) warned of evidence of high usage of low-dose codeine products and associated harms. The memo, referenced by Prof Eamon Keenan, chair of the HSE's codeine working group, highlighted the evidence of harm associated with excessive or prolonged use of low-dose codeine-containing products, including psychological and physical dependence. Serious harms could occur from overexposure to the paracetamol or ibuprofen component of these products when used in excessive doses. According to the memo, the available evidence indicated that combination products with low-dose codeine and paracetamol or ibuprofen were no more effective than paracetamol or ibuprofen alone for managing pain.

To reduce these risks, codeine should be used for the shortest time possible. In general, it is best not to use OTC products for more than three days. Other OTC medicines to be cautious of include decongestants and sedating antihistamines. Decongestants are available as tablets containing pseudoephedrine or as nasal sprays and drops such as xylometazoline and oxymetazoline. Both work by narrowing blood vessels in the nasal passages, reducing swelling and mucus. Long-term overuse of decongestants can damage the lining of the nose, causing dryness, nosebleeds, and, in severe cases, perforation of the nasal wall.

Here are some tips to help you choose OTC products wisely:

  • Ensure your self-diagnosis is as accurate as possible. Avoid assuming the problem is 'something that is going around'.
  • Choose a product based on appropriate ingredients for the condition, not just a familiar brand name.
  • Opt for products with the fewest ingredients. Products claiming to relieve every possible symptom may expose people to unnecessary medications, pose additional risks, and cost more.
  • Carefully read the label to determine the correct dose and take note of any precautions, including medical conditions that could make the medication unsuitable.
  • When in doubt, consult a pharmacist or doctor for the most appropriate product for your symptoms.
  • Ask a pharmacist to check for potential interactions with other medications you are using.
  • Inquire about possible side effects from a pharmacist.
  • Adhere to the recommended dose and do not exceed it.
  • Avoid taking OTC medications for longer than the maximum time suggested on the label. If symptoms worsen, stop taking the medication and seek medical advice.

By following these guidelines, individuals can make informed decisions when choosing OTC medications, ensuring a safe and effective approach to managing their health.

OTC Meds: How to Choose Wisely & Safely! (2026)
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